U Printer is mostly optimized
Key Features
15 Multi-Channel 3D Bio Printing System
15 multi-channel 3D Bio Printing system (Possible to use 15 types of different biomaterials simultaneously + support on 6 simultaneous channel outputs)
Independently-controlled non-contact droplet dispensing for printing low-viscosity biomaterials
Swappable with contact extrusion dispensing heads for the materials with intermediate viscosity range
Embedded LED-based UV (365 nm wavelength – customization possible) crosslinker and shutter control mechanism
Independent printing volume adjustment & temperature control (range 4 – 50 °C)
Simultaneous 6-well printing
Independently-controlled extrusion dispensing for printing high-viscosity biomaterials
Includes injection method for existing 3D Bio Printers ( High Viscosity Extrusion, High Temperature Extrusion, Filament Extrusion) function
UV LED & UV Protection Shutter Technology
Embedded LED-based UV (365 nm wavelength – customization possible) crosslinker and shutter control mechanism
Nebulized Cross-Linking Technology
Independently-controlled crosslinker, based on liquid nebulizer
Works with chemical crosslinking materials in liquid state
Fully automated nebulization
Custom-controlled output power and duration
Specifications
| Nozzle | Bio Materials | U-Printer |
|---|---|---|
| Low-viscosity Microvalve Droplet (Sol) | - Collagen (acidic), Sodium alginate, Fibrinogen etc. - Cross linking Method : pH, Enzymatic, Chemically | ● |
| Low-viscosity Microvalve Extrusion (Sol) | - Gelatin, Agar, UV-activated Hyaluronic Acid etc. - Cross linking Method : UV, Temperature | ● |
| High-viscosity Extrusion | - GelMA gelatin methacryloyl (gel), CollagenMA(Collagen methacryloyl) (gel), HAMA(Hyaluronic acid methacrylate) (gel), Alginate (gel), Agar (gel) etc. - Cross linking Method : UV, Temperature | ● |
| High-viscosity high temperature Extrusion | - PCL(Polycaprolactone), PLGA(Poly lactic-co Glycolic Acid), PLLA(Poly-L-lactic Acid), PLA(poly-lactic acd) etc. : FDA Approved | ● |
| Filament Extrusion | - PCL(Polycaprolactone), PLA(Poly-lactic acid) etc. : Not FDA Approved | ● |
| No. of channels | No. of bio-materials available for constructing an artificial tissue or organ | 15 |
| Dimension/ Weight | 160 x 100 x 200 (w x d x h) cm3/ 160 Kg |
| Housing | Stand-alone biosafety cabinet – Class II/Type A2, equipped with a digital humidity indicator and germicidal UV lamp |
| Swappable modular design | Printing head unit channel 1-6 Printing head unit channel 7-12 High-viscosity extrusion channels 13-14 Polymer filament extruder channel 15 3 nebulization crosslinkers High-intensity UV crosslinker Printing platform |
| Printing head channel 1-6 | Independently-controlled non-contact droplet dispensing for printing low- viscosity biomaterials - Swappable with contact extrusion dispensing heads for the materials with intermediate viscosity range - Embedded LED-based UV (365 nm wavelength – customization possible) crosslinker and shutter control mechanism - Independent printing volume adjustment & temperature control (range 4 – 50 °C) - Simultaneous 6-well printing - Automatic leveling and height adjustment |
| Printing head channel 7-12 | Same as printing head channel 1-6, expansion of the printing options |
| High-viscosity extrusion channels 13-14 | Independently-controlled extrusion dispensing for printing high-viscosity biomaterials - Independent printing volume adjustment & temperature control (range 4 - 50 °C) 13 - Independent printing volume adjustment & high temperature control (range room temperature 150 °C) 14 |
| Polymer filament extruder channel 15 | Fused-deposition-modeling (FDM) type printing of polymer filaments - Front loading extruder for printing low-temperature material such as PCL to regular solid printing such as - Temperature control (range room temperature 260 °C) |
| 3 nebulization crosslinkers | Independently-controlled crosslinker, based on liquid nebulizer - Works with chemical crosslinking materials in liquid state - Fully automated nebulization - Custom-controlled output power and duration |
| High-intensity UV crosslinker | Multi-spectrum, high-power UV crosslinker port using OmnicureTM system - Fully automated operation - Custom-controlled crosslinking duration |
| Printing platform | volume - Temperature control (range 4 – 50 °C) - Built-in head cleaning unit - Customizable bioware dimension (e.g. 6-well/ 6-well with membrane inserts) - Swappable platform for multiplexing options |
| Monitoring cameras | Printing status monitoring camera printing nozzle alignment camera Microscopic camera for on-board cell counting |
| Control computer | Windows 10- based high performance computer with touch screen |
| Control software | Comprehensive printing control interface having; - Independent and simultaneous channel calibration and control - Printing input file compatible with conventional STL format - Built-in printing functions and customizable tool path definition - Visual feedback of printed structures |